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1. An exasperated feeling of annoyance
   - exasperation
    
2. Unfriendly behaviour that causes anger or resentment
   - irritation, provocation
    
3. Action that makes a problem or a disease (or its symptoms) worse
   "the aggravation of her condition resulted from lack of care";
   - exacerbation

Derived forms: aggravations

Type of: aggression, annoyance, chafe, intensification, vexation

Encyclopedia: Aggravation