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Adverb: despairingly  dis'peh-ring-lee
  1. With desperation
    "'Why can't you understand?,' she asked despairingly";
    - despondently

Nearest

Desmond Tutu
desolate
desolately
desolateness
desolation
desorb
desorption
desoxyribonucleic acid
despair
despairing
despairingly
despatch
desperado
desperate
desperate criminal
desperate measure
desperate straits
desperately
desperateness
desperation
despicability