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Adjective: epoch-making  'epuk 'meyking
  1. Highly significant or important especially bringing about or marking the beginning of a new development or era
    "an epoch-making discovery"
    - epochal

See also: important, significant

Nearest

epitomize
epitope
epitrochoidal engine
epizeuxis
epizoan
epizoic
epizoon
epizootic
epoch
epochal
epoch-making
epode
Epona
eponym
eponymic
eponymous
eponymy
epos
epoxy
epoxy glue
epoxy resin