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1. Destroy completely, as if down to the roots
   - uproot, eradicate, root out, exterminate
    
2. Pull up by or as if by the roots
   "extirpate the vine that has spread all over the garden";
   - uproot, deracinate, root out
    
3. (surgery) surgically remove (an organ)

Derived forms: extirpated, extirpates, extirpating

Type of: destroy, destruct, displace, move, remove, spifflicate, spiflicate, take, take away, withdraw

Encyclopedia: Extirpate