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1. Incapable of functioning as a consequence of injury or illness
   - disabled

1. People collectively who are crippled or otherwise physically handicapped
   "technology to help the elderly and the handicapped"
   - disabled

1. Injure permanently
   "He was handicapped in a car accident"
   - disable, invalid, incapacitate
    
2. Attempt to forecast the winner (especially in a horse race) and assign odds for or against a contestant
    
3. Put at a disadvantage
   "The brace I have to wear is handicapping my movements"
   - hinder, hamper

See also: handicapper, unfit

Type of: bias, disadvantage, disfavor [US], disfavour [Brit, Cdn], injure, people, wound

Encyclopedia: Handicap