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Adjective: nettlesome  ne-tl-sum
  1. Causing irritation or annoyance
    "nettlesome paperwork"
    - annoying, bothersome, galling, irritating, pesky, pestering, pestiferous, plaguy, plaguey, teasing, vexatious, vexing
     
  2. Easily irritated or annoyed
    "not the least nettlesome of his countrymen"
    - cranky, fractious, irritable, peevish, peckish, pettish, petulant, scratchy, testy, tetchy, techy, pouty

See also: disagreeable, ill-natured