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Adjective: plaguey  pley-gee
  1. Likely to spread and cause an epidemic disease
    "plaguey fevers";
    - pestilent, pestilential, pestiferous
     
  2. Causing irritation or annoyance
    "a plaguey newfangled safety catch";
    - annoying, bothersome, galling, irritating, nettlesome, pesky, pestering, pestiferous, plaguy, teasing, vexatious, vexing
Adverb: plaguey  pley-gee
  1. In a disagreeable manner
    "it's so plaguey cold!";
    - plaguy, plaguily

See also: disagreeable, epidemic