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Adverb: upstream  'úp'streem
  1. Toward the source or against the current
    - upriver
Adjective: upstream  'úp'streem
  1. In the direction against a stream's current
     
  2. In the direction towards the source of a signal; at a higher level
    "The messages are transmitted to dendrites by upstream neurons via synapses"

Antonym: downstream

Encyclopedia: Upstream

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upsilon
upskill
upslope
upstage
upstager
upstair
upstairs
upstanding
upstart
upstate
upstream
upstroke
upsurge
upsweep
upswept
upswing
upsy-daisy
uptake
upthrow
upthrust
uptick