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Adverb: upstream  'úp'streem
  1. Toward the source or against the current
    "went upstream to look at a sure-enough fish wheel";
    - upriver
Adjective: upstream  'úp'streem
  1. In the direction against a stream's current
  2. In the direction towards the source of a signal; at a higher level
    "The messages are transmitted to dendrites by upstream neurons via synapses"

Antonym: downstream

Encyclopedia: Upstream