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1. Remove, destroy or wipe out completely
   - uproot, eradicate, root out, exterminate
    
2. Pull up by or as if by the roots
   "extirpate the vine that has spread all over the garden";
   - uproot, deracinate [formal], root out
    
3. (surgery) surgically remove (an organ)

Derived forms: extirpating, extirpated, extirpates

Type of: destroy, destruct, displace, move, remove, spifflicate [Brit, informal], spiflicate [Brit, informal], take, take away, uncreate [literary], withdraw

Encyclopedia: Extirpate