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Verb: incapacitate  ,in-ku'pa-su,teyt
  1. Make unable to perform a certain action
    "incapacitate this command on your computer";
    - disable, disenable
  2. Injure permanently
    "He was incapacitated in a car accident";
    - disable, invalid, handicap

Derived forms: incapacitated, incapacitates, incapacitating

Type of: alter, change, injure, modify, wound

Antonym: enable