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Adjective: unwholesome  ,ún'hówl-sum
  1. Detrimental to physical or moral well-being
    "unwholesome food"; "unwholesome habits like smoking"

See also: harmful, insalubrious, insubstantial, loathful [archaic], loathsome, morbid, nauseating, nauseous, noisome, noxious, offensive, queasy, rich, sickening, unhealthful, unhealthy, unsound, vile, vomitous [US]

Antonym: wholesome