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Noun: ups and downs
Usage: informal
  1. Periods of positive and negative events, moods or interactions

Encyclopedia: Ups and downs

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uprightness
uprise
uprising
upriver
uproar
uproarious
uproariously
uproot
uprooter
uprush
ups and downs
ups-a-daisy
Upsala
upscale
upsell
upset
upset price
upset stomach
upsetter
upsetting
upshot