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Adjective: nettlesome  ne-t(u)l-sum
  1. Causing irritation or annoyance
    "nettlesome paperwork";
    - annoying, bothersome, galling, irritating, pesky [informal], pestering, pestiferous, plaguy, plaguey, teasing, vexatious, vexing, irksome, niggly, dratted [informal]
  2. Easily irritated or annoyed
    "not the least nettlesome of his countrymen";
    - cranky [informal], fractious, irritable, peevish, peckish [N. Amer, informal], pettish, petulant, scratchy, testy, tetchy, techy, pouty, narky [Brit, slang]

See also: disagreeable, ill-natured