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Adjective: operose
  1. Characterized by effort to the point of exhaustion; especially physical effort
    "worked their operose way up the mining valley"
    - arduous, backbreaking, grueling [US], gruelling [Brit, Cdn], hard, heavy, laborious, punishing, toilsome

See also: effortful, operoseness

Nearest

operative field
operatively
operator
operator gene
opercular
operculate
operculated
operculum
operetta
operon
operose
operoseness
Opheodrys
Opheodrys aestivus
Opheodrys vernalis
Ophidia
ophidian
Ophidiidae
ophidism
Ophiodon
Ophiodon elongatus