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Adjective: out of it
Usage: Brit
  1. Very drunk
    - besotted [archaic], blind drunk, blotto, crocked [N. Amer], cockeyed, fuddled, loaded [N. Amer], pie-eyed, pixilated, plastered, slopped, sloshed, smashed, soaked, soused, sozzled, squiffy, stiff, tight, wet, blitzed, mullered [Brit], trolleyed [Brit], legless [Brit], stewed, tanked up, liquored up [N. Amer], bombed, trashed, wasted, paralytic [Brit], three sheets to the wind, stonkered [Austral, NZ], pickled, juiced [N. Amer], stinko, hammered, bladdered [Brit], bevvied [Brit], drunk, pixillated, squiffed

See also: drunk, inebriated, intoxicated